Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | FDPS | P14324 | 1/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821280 | 1.00 | EPHX2 (0.66) | EPHX2FDPSTUBB1KDM4EALDH1A1 | |
| SCHEMBL584263 | 0.86 | KDM4E (0.73) | TUBB1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29090925 | 0.86 | TUBB1 (0.66) | FDPSTUBB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL584262 | 0.86 | KDM4E (0.73) | TUBB1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30548412 | 0.86 | TUBB1 (0.66) | FDPSTUBB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24164775 | 0.86 | TUBB1 (0.66) | FDPSTUBB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20158247 | 0.85 | TUBB1 (0.59) | EPHX2FDPSTUBB1KDM4EALDH1A1 | |
| SCHEMBL30594189 | 0.85 | FDPS (0.70) | FDPSTUBB1TTRCA12CA1 | |
| SCHEMBL3678457 | 0.85 | FDPS (0.70) | FDPSTUBB1TTRCA12CA1 | |
| SCHEMBL30487467 | 0.85 | TUBB1 (0.59) | EPHX2FDPSTUBB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |