SCHEMBL6821328

SCHEMBL6821328

Cc1cccc(Nc2sc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(OC4CCN(C)C4)c3)cc2[N+](=O)[O-])c1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 16/20 0.51
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GHSR Q92847 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6821321 1.00 UTS2R (0.51) UTS2RL3MBTL1MEN1KMT2AGHSR
SCHEMBL6817552 0.87 UTS2R (0.51) UTS2R
SCHEMBL6817542 0.87 UTS2R (0.51) UTS2R
SCHEMBL8342189 0.86 UTS2R (0.59) UTS2R
SCHEMBL6815846 0.84 UTS2R (0.57) UTS2R
SCHEMBL6815857 0.84 UTS2R (0.57) UTS2R
SCHEMBL8342604 0.84 UTS2R (0.57) UTS2R
SCHEMBL6821322 0.83 UTS2R (0.55) UTS2R
SCHEMBL6821330 0.83 UTS2R (0.55) UTS2R
SCHEMBL8340971 0.82 UTS2R (0.55) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed