Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7169192 | 0.99 | CYP19A1 (0.49) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL6822439 | 0.90 | CYP19A1 (0.52) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL6827784 | 0.82 | CYP19A1 (0.65) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL6827715 | 0.80 | CYP19A1 (0.54) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL6825253 | 0.78 | CYP19A1 (0.44) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| SCHEMBL7457634 | 0.75 | CYP19A1 (0.48) | CYP19A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6825612 | 0.74 | CYP19A1 (0.53) | CYP19A1CYP11B2ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7453886 | 0.74 | CYP19A1 (0.47) | CYP19A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6822431 | 0.69 | CYP11B2 (0.63) | CYP19A1CYP11B2CYP17A1CYP11B1 | |
| SCHEMBL3847255 | 0.68 | ESR1 (0.52) | CYP19A1CYP11B2ALDH1A1SMN1; SMN2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028110-B1 | NOVEL DIHYDRONAPHTHALENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | DAIICHI SEIYAKU CO (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-6559157-B2 | Excellent 17 alpha - hydroxylase/C17-20-lyase and aromatase inhibiting activity, thromboxan A2 synthesis inhibiting activity, useful as preventive and/or therapeutic agents for various male and female sex hormone dependent diseases | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |