Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6825781 | 0.98 | MAPK1 (0.31) | MAPK1KLKB1POLB | |
| SCHEMBL31759486 | 0.85 | MAPK1 (0.32) | MAPK1KLKB1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL6826099 | 0.78 | ADORA2A (0.43) | L3MBTL1KDM4E | |
| SCHEMBL30900609 | 0.74 | PIM3 (0.39) | MAPK1POLBL3MBTL1KDM4E | |
| SCHEMBL8092354 | 0.73 | — | — | |
| SCHEMBL18965268 | 0.69 | — | — | |
| SCHEMBL8087667 | 0.65 | ALDH1A1 (0.35) | SMN1; SMN2KDM4E | |
| SCHEMBL6826054 | 0.60 | SMYD3 (0.40) | POLBL3MBTL1KDM4E | |
| SCHEMBL6825782 | 0.60 | PLA2G10 (0.45) | MAPK1POLBL3MBTL1DPP4DPP8 | |
| SCHEMBL1088195 | 0.60 | MAPK1 (0.48) | MAPK1POLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |