Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822956 | 1.00 | TDP1 (0.50) | TDP1HTTRECQLMAPTLMNA | |
| SCHEMBL27746307 | 0.78 | TDP1 (0.48) | TDP1HTTRECQLMAPTLMNA | |
| SCHEMBL2043304 | 0.78 | — | — | |
| SCHEMBL158198 | 0.78 | — | — | |
| SCHEMBL13887197 | 0.76 | TDP1 (0.46) | TDP1HTTRECQLMAPTLMNA | |
| SCHEMBL10418299 | 0.76 | TDP1 (0.46) | TDP1HTTRECQLMAPTLMNA | |
| SCHEMBL932496 | 0.76 | TDP1 (0.46) | TDP1HTTRECQLMAPTLMNA | |
| Ammonia Solution, Strong SCHEMBL7051918 | 0.76 | — | — | |
| SCHEMBL932497 | 0.76 | TDP1 (0.46) | TDP1HTTRECQLMAPTLMNA | |
| Chloromethane SCHEMBL1334446 | 0.74 | TDP1 (0.56) | TDP1HTTRECQLMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | claimed |
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | disclosed |