Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823026 | 1.00 | UTS2R (0.64) | UTS2RHTR2CHTR2BHSD17B3HSD17B2 | |
| SCHEMBL8342919 | 0.92 | UTS2R (0.66) | UTS2RHTR2CHTR2BALDH1A1HTR6 | |
| SCHEMBL8342926 | 0.91 | UTS2R (0.65) | UTS2RHTR2CHTR2BALDH1A1POLB | |
| SCHEMBL8342609 | 0.90 | UTS2R (0.64) | UTS2RHTR2CALDH1A1HTR6DRD2 | |
| SCHEMBL8340488 | 0.90 | UTS2R (0.69) | UTS2RHTR2CHTR2BALDH1A1HTR6 | |
| SCHEMBL5835420 | 0.89 | UTS2R (0.61) | UTS2RHTR2CHTR2BALDH1A1SMN1; SMN2 | |
| SCHEMBL8342415 | 0.89 | UTS2R (0.61) | UTS2RHTR6MEN1KMT2A | |
| SCHEMBL5835413 | 0.89 | UTS2R (0.61) | UTS2RHTR2CHTR2BALDH1A1SMN1; SMN2 | |
| SCHEMBL5835458 | 0.89 | UTS2R (0.63) | UTS2RALDH1A1PKMSMN1; SMN2HTR6 | |
| SCHEMBL5835453 | 0.89 | UTS2R (0.63) | UTS2RALDH1A1PKMSMN1; SMN2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |