Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 12/20 | 0.69 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342919 | 0.92 | UTS2R (0.66) | UTS2RHTR6CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8342926 | 0.91 | UTS2R (0.65) | UTS2RCYP1A2CYP3A4CYP2D6HTR2C | |
| SCHEMBL5834811 | 0.90 | UTS2R (0.70) | UTS2RHTR6MAPTMEN1LMNA | |
| SCHEMBL5834807 | 0.90 | UTS2R (0.70) | UTS2RHTR6MAPTMEN1LMNA | |
| SCHEMBL6823026 | 0.90 | UTS2R (0.64) | UTS2RHTR6DRD2HTR2AHTR2C | |
| SCHEMBL6823022 | 0.90 | UTS2R (0.64) | UTS2RHTR6DRD2HTR2AHTR2C | |
| SCHEMBL8342609 | 0.90 | UTS2R (0.64) | UTS2RHTR6CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5835458 | 0.89 | UTS2R (0.63) | UTS2RHTR6DRD2DRD3MAPT | |
| SCHEMBL5835453 | 0.89 | UTS2R (0.63) | UTS2RHTR6DRD2DRD3MAPT | |
| SCHEMBL5835336 | 0.88 | UTS2R (0.62) | UTS2RHTR6CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |