Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826862 | 0.88 | NPY5R (0.61) | NPY5RMAPK8EPHX2KMT2A | |
| SCHEMBL6824384 | 0.86 | NPY5R (0.59) | NPY5RNPC1RAB9A | |
| SCHEMBL6823457 | 0.85 | NPY5R (0.62) | NPY5REPHX2KMT2A | |
| SCHEMBL6826590 | 0.81 | NPY5R (0.60) | NPY5RRAB9AKMT2A | |
| SCHEMBL6826986 | 0.81 | NPY5R (0.67) | NPY5RNPC1RAB9A | |
| SCHEMBL6829275 | 0.81 | NPY5R (0.69) | NPY5RNPC1RAB9AKMT2A | |
| SCHEMBL6826749 | 0.78 | NPY5R (0.65) | NPY5RRAB9AKMT2A | |
| SCHEMBL6828937 | 0.76 | NPY5R (0.67) | NPY5RKMT2A | |
| SCHEMBL6829107 | 0.75 | NPY5R (0.64) | NPY5RKMT2A | |
| SCHEMBL6823308 | 0.74 | NPY5R (0.62) | NPY5RNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | ASTRAZENECA AB (SE) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | NPY5R, NPY1R, NPY2R | NPY5R 1/4885PARP1 1906/4885PARP2 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.