SCHEMBL6823531

SCHEMBL6823531

C[C@@]1(Oc2cc(NS(=O)(=O)c3cc(Br)c(Sc4cccc(Cl)c4Cl)s3)ccc2C(F)(F)F)CCNC1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ UTS2R Q9UKP6 8/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6821327 0.94 UTS2R (0.35) UTS2R
SCHEMBL6821099 0.89 UTS2R (0.33) UTS2R
SCHEMBL6820782 0.88 SMN1; SMN2 (0.33) UTS2R
SCHEMBL6821386 0.87 UTS2R (0.36) UTS2R
SCHEMBL6823458 0.87 UTS2R (0.36) UTS2R
SCHEMBL6823505 0.86 UTS2R (0.36) UTS2R
SCHEMBL6824519 0.86 TP53 (0.37) UTS2R
SCHEMBL6820785 0.85 UTS2R (0.36) UTS2R
SCHEMBL6821340 0.85 UTS2R (0.36) UTS2R
SCHEMBL6820770 0.84 UTS2R (0.37) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 — — WO claimed
WO-2004043917-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 — — WO disclosed
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