Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322781 | 0.91 | DPP8 (0.44) | DPP4DPP8ITGB3ITGA2BDPP9 | |
| SCHEMBL10730573 | 0.91 | DPP8 (0.44) | DPP4DPP8ITGB3ITGA2BDPP9 | |
| Trifluoroacetic Acid SCHEMBL6824018 | 0.80 | DPP7 (0.51) | DPP4DPP8ITGB3ITGA2BDPP9 | |
| Trifluoroacetic Acid SCHEMBL31651399 | 0.80 | NPY4R (0.40) | DPP7 | |
| Arginine SCHEMBL29664038 | 0.80 | OTC (0.48) | ARG1 | |
| Arginine SCHEMBL7432633 | 0.80 | OTC (0.48) | ARG1 | |
| Arginine SCHEMBL7443448 | 0.80 | OTC (0.48) | ARG1 | |
| Trifluoroacetic Acid SCHEMBL6826306 | 0.79 | DPP7 (0.52) | DPP4DPP8ITGB3ITGA2BDPP9 | |
| Trifluoroacetic Acid SCHEMBL6820621 | 0.79 | DPP4 (0.46) | DPP4DPP8ITGB3ITGA2BDPP9 | |
| Trifluoroacetic Acid SCHEMBL6820622 | 0.79 | DPP7 (0.52) | DPP4DPP8ITGB3ITGA2BDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |