Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.69 |
| ▸ | KDR | P35968 | 11/20 | 0.69 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279077 | 0.88 | SRC (0.77) | SRCKDREGFR | |
| SCHEMBL6919929 | 0.87 | SRC (0.81) | SRCKDREGFR | |
| SCHEMBL6824096 | 0.86 | SRC (0.83) | SRCKDREGFR | |
| SCHEMBL3277252 | 0.84 | SRC (0.62) | SRCKDREGFR | |
| SCHEMBL3275554 | 0.84 | SRC (0.59) | SRCKDREGFRMKNK2 | |
| SCHEMBL3275923 | 0.82 | SRC (0.70) | SRCKDREGFR | |
| SCHEMBL7065934 | 0.81 | SRC (0.91) | SRCKDREGFR | |
| SCHEMBL6819634 | 0.80 | SRC (0.61) | SRCKDREGFRMKNK2 | |
| SCHEMBL6922967 | 0.80 | SRC (0.78) | SRCKDREGFR | |
| SCHEMBL3276553 | 0.78 | SRC (0.69) | SRCKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056801-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |