Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.81 |
| ▸ | KDR | P35968 | 12/20 | 0.81 |
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | GAK | O14976 | 1/20 | 0.53 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | STK10 | O94804 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | YES1 | P07947 | 1/20 | 0.53 |
| ▸ | LYN | P07948 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | HCK | P08631 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | FGR | P09769 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824096 | 0.97 | SRC (0.83) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL7065934 | 0.88 | SRC (0.91) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL6823680 | 0.87 | SRC (0.69) | SRCKDREGFR | |
| SCHEMBL6921967 | 0.86 | SRC (0.81) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL6922967 | 0.85 | SRC (0.78) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL6920379 | 0.83 | SRC (0.83) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL6923526 | 0.82 | SRC (0.72) | SRCKDREGFR | |
| SCHEMBL6831114 | 0.81 | SRC (0.81) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL3205210 | 0.79 | EGFR (0.53) | SRCKDREGFRBMPR1BGAK | |
| SCHEMBL3197017 | 0.79 | SRC (0.65) | SRCKDREGFRBMPR1BGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056801-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |