Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.44 |
| ▸ | LIPC | P11150 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5743521 | 0.99 | CNR2 (0.47) | CNR2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3713690 | 0.92 | CNR2 (0.54) | CNR2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL477819 | 0.83 | LIPG (0.54) | CNR2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL477818 | 0.83 | LIPG (0.54) | CNR2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5743525 | 0.81 | UTS2R (0.44) | CNR2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10370107 | 0.81 | HTR2C (0.56) | — | |
| SCHEMBL6636434 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1MAPTSMN1; SMN2CHRM4 | |
| SCHEMBL10370921 | 0.79 | KCNH2 (0.52) | KDM4ESMN1; SMN2CHRM4CHRM3 | |
| SCHEMBL10565941 | 0.78 | HTR2C (0.51) | CNR2MAPTSMN1; SMN2CHRM4CHRM3 | |
| SCHEMBL5742176 | 0.77 | UTS2R (0.51) | KDM4EMAPTSCDLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |