Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 12/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823990 | 1.00 | UTS2R (0.57) | UTS2RCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6821285 | 0.94 | UTS2R (0.61) | UTS2RCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6821277 | 0.94 | UTS2R (0.61) | UTS2RCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL8342830 | 0.88 | UTS2R (0.64) | UTS2RCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6823983 | 0.87 | UTS2R (0.64) | UTS2RALDH1A1 | |
| SCHEMBL6823993 | 0.87 | UTS2R (0.64) | UTS2RALDH1A1 | |
| SCHEMBL6821363 | 0.87 | UTS2R (0.63) | UTS2RSCD | |
| SCHEMBL6823471 | 0.87 | UTS2R (0.63) | UTS2RSMN1; SMN2 | |
| SCHEMBL6823477 | 0.87 | UTS2R (0.63) | UTS2RSMN1; SMN2 | |
| SCHEMBL6821370 | 0.87 | UTS2R (0.63) | UTS2RSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |