Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6825183 | 0.88 | CACNA1B (0.53) | CACNA1B | |
| Hydrochloric Acid SCHEMBL6823875 | 0.85 | CACNA1B (0.56) | CACNA1B | |
| Hydrochloric Acid SCHEMBL6820404 | 0.84 | CACNA1B (0.55) | CACNA1B | |
| Hydrochloric Acid SCHEMBL6824360 | 0.80 | CACNA1B (0.54) | CACNA1B | |
| SCHEMBL6823921 | 0.72 | CACNA1B (0.64) | CACNA1B | |
| SCHEMBL6920684 | 0.72 | CACNA1B (0.72) | CACNA1B | |
| SCHEMBL6823594 | 0.72 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL6823908 | 0.70 | CACNA1B (0.70) | CACNA1B | |
| SCHEMBL6824063 | 0.70 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL6820500 | 0.70 | CACNA1B (1.00) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017966-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS IN THE TREATMENT OF CHRONIC AND ACUTE PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | claimed |