Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823654 | 0.97 | MAPK14 (0.34) | MAPK14PIK3CALOXL2KMT2AMEN1 | |
| SCHEMBL6824151 | 0.92 | IKBKB (0.34) | LOXL2KMT2AMEN1HSD17B14PDGFRB | |
| SCHEMBL6920876 | 0.91 | KMT2A (0.33) | LOXL2KMT2AMEN1HSD17B14HDAC1 | |
| SCHEMBL6824690 | 0.91 | IKBKB (0.35) | LOXL2KMT2AMEN1HSD17B14PDGFRB | |
| SCHEMBL6921921 | 0.91 | CDK1 (0.34) | LOXL2KMT2AMEN1HSD17B14HDAC1 | |
| SCHEMBL6826558 | 0.90 | HSD17B14 (0.32) | LOXL2KMT2AMEN1HSD17B14PDGFRB | |
| SCHEMBL6824066 | 0.86 | HSD17B14 (0.32) | KMT2AMEN1HSD17B14CDK1CDK2 | |
| SCHEMBL6823887 | 0.86 | CDK2 (0.37) | MAPK14KMT2AMEN1HSD17B14KDM4E | |
| SCHEMBL6821385 | 0.85 | MAPK14 (0.34) | MAPK14KDRCDK1CDK2 | |
| SCHEMBL6824190 | 0.84 | MAPK14 (0.43) | MAPK14KDRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |