SCHEMBL6824311

SCHEMBL6824311

N#Cc1cccc(CNCC[C@H](N)C(=O)N2CCCCC2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 20/20 1.00
DPP4 P27487 6/20 0.53
DPP8 Q6V1X1 2/20 0.50
DPP9 Q86TI2 2/20 0.50
FAP Q12884 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824310 1.00 DPP7 (1.00) DPP7DPP4DPP8DPP9FAP
SCHEMBL8385358 0.84 DPP7 (0.72) DPP7DPP4DPP8DPP9FAP
SCHEMBL6824340 0.76 DPP7 (0.77) DPP7DPP4DPP8
SCHEMBL3843671 0.75 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP
SCHEMBL19923030 0.75 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP
SCHEMBL19923028 0.75 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP
SCHEMBL1336061 0.73 DPP7 (0.58) DPP7DPP4DPP8DPP9FAP
SCHEMBL7062524 0.73 DPP7 (0.72) DPP7DPP4
SCHEMBL18049272 0.73 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP
SCHEMBL18049369 0.73 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076434-A1 DIPEPTIDYL PEPTIDASE INHIBITORS AIC (BE) 2004-09-10 WO disclosed