SCHEMBL682465

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL682821	1.00	HDAC8 (0.45)	HDAC8MEN1KMT2ATACR2DDB1
	SCHEMBL2088808	1.00	HDAC8 (0.45)	HDAC8MEN1KMT2ATACR2DDB1
	SCHEMBL18577316	0.83	CMA1 (0.39)	MEN1KMT2ACXCR4F2PRSS1
	SCHEMBL18577318	0.83	CMA1 (0.39)	MEN1KMT2ACXCR4F2PRSS1
	SCHEMBL4551372	0.83	TACR2 (0.40)	HDAC8TACR2
	SCHEMBL3878053	0.83	GAA (0.41)	TACR2POLBCXCR4
	SCHEMBL21180342	0.82	CXCR4 (0.37)	CXCR4
	SCHEMBL9114436	0.81	F2 (0.45)	POLBGBA1F2PRSS1
	SCHEMBL13427805	0.79	MEN1 (0.42)	MEN1KMT2APOLBGBA1
	SCHEMBL7385157	0.76	HDAC8 (0.47)	HDAC8DDB1CRBNPOLBGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.