Ragaglitazar

Ragaglitazar

SCHEMBL6824729

CCNc1ccccc1.CCO[C@@H](Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)cc1)C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.86
PPARA Q07869 18/20 0.86
PPARD Q03181 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ragaglitazar SCHEMBL6281098 1.00 PPARG (0.86) PPARGPPARAPPARD
Ragaglitazar SCHEMBL682732 0.93 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL4822459 0.93 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL676872 0.93 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL29369224 0.93 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL6280349 0.92 PPARG (0.81) PPARGPPARAPPARD
Ragaglitazar SCHEMBL6281845 0.91 PPARG (0.80) PPARGPPARAPPARD
Ragaglitazar SCHEMBL6283531 0.88 PPARG (0.91) PPARGPPARAPPARD
Ragaglitazar SCHEMBL6283288 0.87 PPARG (0.89) PPARGPPARAPPARD
Ragaglitazar SCHEMBL6281839 0.87 PPARG (0.89) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004063178-A1 PROCESS FOR THE PREPARATION OF ANTIDIABETIC PHENOXAZINE COMPOUNDS DR. REDDY'S LABORATORIES LTD. (IN) 2004-07-29 WO disclosed