Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 1.00 |
| ▸ | PPARG | P37231 | 17/20 | 1.00 |
| ▸ | PPARD | Q03181 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ragaglitazar SCHEMBL676872 | 1.00 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL4822459 | 1.00 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL29369224 | 1.00 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6283531 | 0.95 | PPARG (0.91) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6283288 | 0.94 | PPARG (0.89) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6281839 | 0.94 | PPARG (0.89) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6281098 | 0.93 | PPARG (0.86) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6281101 | 0.93 | PPARG (0.86) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6820225 | 0.93 | PPARG (0.86) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL6824727 | 0.93 | PPARG (0.86) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338480-B2 | Combination treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-12-25 | — | — | US | claimed |
| WO-2012158123-A1 | COMPOUNDS AND METHODS FOR TREATING INSULIN RESISTANCE SYNDROME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-11-22 | — | — | WO | claimed |
| US-20100292277-A1 | COMBINATION TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-11-18 | — | — | US | claimed |
| EP-2001461-A2 | COMBINATION TREATMENT OF METABOLIC DISORDERS | Wellstat Therapeutics Corporation (US) | 2008-12-17 | — | — | EP | claimed |
| EP-1949908-A1 | Combined use of derivatives of GLP-1 analogs and PPAR ligands | NOVO NORDISK A/S (DK) | 2008-07-30 | — | — | EP | claimed |
| US-20080070867-A1 | 2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases | METABASIS THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | claimed |
| WO-2007117791-A2 | COMBINATION TREATMENT OF METABOLIC DISORDERS | WELLSTAT THERAPEUTICS CORPORATION (US) | 2007-10-18 | — | — | WO | claimed |
| US-20050070536-A1 | Novel tablets and capsules and a process for its preparation | DR. REDDY'S LABORATORIES, INC. | 2005-03-31 | — | — | US | claimed |
| EP-1370244-A1 | NOVEL TABLETS AND CAPSULES AND A PROCESS FOR ITS PREPARATION | NOVO NORDISK A/S (DK) | 2003-12-17 | — | — | EP | claimed |
| EP-1368055-A2 | COMBINED USE OF DERIVATIVES OF GLP-1 ANALOGS AND PPAR LIGANDS | NOVO NORDISK A/S (DK) | 2003-12-10 | — | — | EP | claimed |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY- CHEMINOR, INC. | 2002-06-20 | — | — | US | claimed |
| WO-2000063193-A9 | NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | REDDY RESEARCH FOUNDATION (IN) | 2002-04-04 | — | — | WO | claimed |
| EP-1155006-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Dr. Reddy's Research Foundation (IN) | 2001-11-21 | — | — | EP | claimed |
| CN-1280575-A | Novel tricyclic compounds and their use as medicaments, process for their preparation and pharmaceutical compositions containing them | REDDY CHEMINOR INC (IN) | 2001-01-17 | — | — | CN | claimed |
| EP-1049684-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-08 | — | — | EP | claimed |
| WO-2000063191-A1 | NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-10-26 | — | — | WO | claimed |
| WO-2000063193-A1 | NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-10-26 | — | — | WO | claimed |
| WO-2000050414-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR.REDDY'S RESEARCH FOUNDATION (IN) | 2000-08-31 | — | — | WO | claimed |
| US-6054453-A | HYPOLIPIDEMIC, ANTIHYPERGLYCEMIC USES. | REDD'S RESEARCH FOUNDATION (IN) | 2000-04-25 | — | — | US | claimed |
| WO-1999019313-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070867-A1 | 2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases | PPM1B, PPM1D, PTPRS | PPARA 2456/4885PPARG 1818/4885PPARD 1972/4885 |
| US-20100292277-A1 | COMBINATION TREATMENT OF METABOLIC DISORDERS | NR1H3, GPR119, NR1H2 | PPARA 13/4885PPARG 12/4885PPARD 7/4885 |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | LIPC, GPR119, CPT1A | PPARA 281/4885PPARG 102/4885PPARD 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.