Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455888 | 1.00 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL1068731 | 1.00 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| Water SCHEMBL27304038 | 0.98 | PLA2G2A (0.54) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| Water SCHEMBL4794958 | 0.98 | PLA2G2A (0.54) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL30174895 | 0.95 | PLA2G2A (0.57) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL16124610 | 0.95 | PLA2G2A (0.57) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL7771256 | 0.94 | PLA2G2A (0.60) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL7771206 | 0.94 | PLA2G2A (0.60) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL16124633 | 0.94 | PLA2G2A (0.60) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 | |
| SCHEMBL7771259 | 0.94 | PLA2G2A (0.60) | PLA2G2APLA2G5ALDH1A1FOLH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |