SCHEMBL6824879

SCHEMBL6824879

CCOC(=O)c1ccc2occc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 7/20 0.58
WNT3A P56704 7/20 0.58
TAS1R3 Q7RTX0 1/20 0.55
TAS1R1 Q7RTX1 1/20 0.55
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
HTR1B P28222 1/20 0.51
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
HSD17B2 P37059 1/20 0.48
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAOA P21397 1/20 0.47
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL827792 0.88 CA12 (0.53) CTNNB1WNT3ACA12CA1CA2
SCHEMBL2491600 0.85 CTNNB1 (0.56) CTNNB1WNT3ATAS1R3TAS1R1CA12
SCHEMBL22819676 0.84 CTNNB1 (0.52) CTNNB1WNT3ATAS1R3TAS1R1HTR1B
SCHEMBL13516246 0.82 CTNNB1 (0.60) CTNNB1WNT3ATAS1R3TAS1R1HTR1B
SCHEMBL14399373 0.82 TAS1R3 (0.48) CTNNB1WNT3ATAS1R3TAS1R1CA2
SCHEMBL826046 0.82 HTR1B (0.59) CTNNB1WNT3ATAS1R3TAS1R1CA12
SCHEMBL14369817 0.82 CTNNB1 (0.50) CTNNB1WNT3ATAS1R3TAS1R1HTR1B
Hydrochloric Acid SCHEMBL29696055 0.81 HTR1B (0.57) CTNNB1WNT3ATAS1R3TAS1R1CA12
SCHEMBL27540475 0.80 CTNNB1 (0.58) CTNNB1WNT3ALMNACYP3A4MAPT
SCHEMBL707407 0.79 CA12 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504431-A Method for esterification of carboxylic acid and continuous flow photochemistry device 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN disclosed
CN-119504430-A Carboxylic acid esterification method and gas-liquid mixed flow photochemical device 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN disclosed
CN-108884083-B Benzo [ B ] furans as bromodomain inhibitors 葛兰素史克知识产权第二有限公司 2022-02-25 CN disclosed
CN-109641908-A Five-ring heterocycles simultaneously [3,4-d] pyridazinone compound, preparation method, pharmaceutical composition and its application 中国科学院上海药物研究所 2019-04-16 CN disclosed
CN-107417687-A Five-ring heterocycles simultaneously [3,4 d] pyridazinone compound, its preparation method, pharmaceutical composition and its application 中国科学院上海药物研究所 2017-12-01 CN disclosed
WO-2004069840-A2 PRODUCTION OF TETRAHYDROQUINOLINE BENZOFURANS Grünenthal GmbH (DE) 2004-08-19 WO disclosed