Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 1.00 |
| ▸ | ESR1 | P03372 | 10/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853599 | 0.84 | ESR2 (0.73) | ESR2ESR1HSD17B10POLBMAPT | |
| SCHEMBL26766950 | 0.84 | ESR2 (0.73) | ESR2ESR1HSD17B10POLBMAPT | |
| SCHEMBL12813762 | 0.84 | ESR2 (0.72) | ESR2ESR1HSD17B10POLBMAPT | |
| SCHEMBL11843906 | 0.82 | ESR2 (0.70) | ESR2ESR1HSD17B10POLBMAPT | |
| SCHEMBL6828078 | 0.82 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL6825648 | 0.82 | ESR2 (0.77) | ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL22413028 | 0.81 | ESR2 (0.77) | ESR2ESR1 | |
| SCHEMBL6825403 | 0.79 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL6828126 | 0.79 | ESR2 (0.73) | ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL29853560 | 0.79 | KDM4E (0.79) | ESR2ESR1HSD17B10POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |
| EP-2691542-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | Trana Discovery, Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| WO-2012135416-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |