Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 0.73 |
| ▸ | ESR1 | P03372 | 13/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828078 | 0.84 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825648 | 0.84 | ESR2 (0.77) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825403 | 0.82 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6825266 | 0.81 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL22431062 | 0.80 | ESR2 (0.76) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6824968 | 0.79 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1 | |
| SCHEMBL6828637 | 0.78 | ESR2 (1.00) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL22413393 | 0.78 | ESR2 (0.71) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL3766383 | 0.77 | KDM4E (0.74) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL6830085 | 0.76 | ESR2 (0.68) | ESR2ESR1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | claimed |