SCHEMBL6824993

SCHEMBL6824993

N#Cc1c(-c2ccccc2)cc(-c2ccccc2)c(C#N)c1N

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.71
HPGD P15428 5/20 0.71
KDM4E B2RXH2 4/20 0.71
HSD17B10 Q99714 3/20 0.71
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
MAPK1 P28482 3/20 0.71
MAPT P10636 2/20 0.71
GAA P10253 2/20 0.71
USP2 O75604 1/20 0.71
ESR1 P03372 1/20 0.71
POLB P06746 1/20 0.71
ALOX15 P16050 1/20 0.71
CASP1 P29466 1/20 0.71
BLM P54132 1/20 0.71
CASP7 P55210 1/20 0.71
ADORA1 P30542 8/20 0.61
ADORA2A P29274 8/20 0.61
L3MBTL1 Q9Y468 2/20 0.51
PIM1 P11309 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26869235 0.89 KDM4E (0.60) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL27539129 0.87 HPGD (0.58) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL3480568 0.83 PTPN1 (0.54) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL27281983 0.82 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL28921509 0.82 ALDH1A1 (0.52) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL3154061 0.80 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL22785937 0.79 ADORA1 (0.51) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL16122425 0.79 ADORA1 (0.51) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL31070133 0.79 ALDH1A1 (0.49) ALDH1A1HPGDKDM4EHSD17B10MEN1
SCHEMBL28795473 0.79 ADORA1 (0.51) ALDH1A1HPGDKDM4EHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219521-A1 NEW 2-(DIETHYLAMINO)-4,6-DIPHENYLBENZENE-1,3-CARBONITRILE DERIVATIVES, METHOD OF THEIR PRODUCTION, THEIR USE AND NEW PHOTOINITIATING SYSTEMS FOR PHOTOINITIATED CATIONIC, RADICAL, THIOL-ENE AND HYBRID POLYMERIZATION Politechnika Krakowska im. Tadeusza Kościuszki (PL) 2023-11-16 WO disclosed
US-20040195552-A1 useful as powders or pellets for incorporation into a variety of thermoplastic resins; diacidic anthraquinone compounds WEAVER MAX ALLEN (US) 2004-10-07 US disclosed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US disclosed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US disclosed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US disclosed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A9 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS 1998-09-17 WO disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed