Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29761429 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL30101200 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28502999 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8027943 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL31386984 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL22049 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29482291 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL23275594 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL1203399 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8571476 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-07-05 | — | — | US | disclosed |
| US-8129111-B2 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-03-06 | — | — | US | disclosed |
| US-7939613-B2 | Probes/sensors for biomacromolecules; films; cosmetics | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |