Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825164 | 0.90 | HDAC6 (0.49) | HDAC6HDAC1HDAC8ALDH1A1HTT | |
| SCHEMBL6825085 | 0.88 | HDAC1 (0.46) | HDAC6HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6923084 | 0.87 | HDAC1 (0.46) | HDAC6HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6825473 | 0.83 | HDAC6 (0.48) | HDAC6HDAC1HDAC8ALDH1A1HTT | |
| SCHEMBL6825934 | 0.83 | KMT2A (0.44) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6922062 | 0.82 | SMN1; SMN2 (0.38) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6825108 | 0.82 | NPC1 (0.47) | ALDH1A1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL6822282 | 0.80 | ANPEP (0.45) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL6825780 | 0.80 | HDAC1 (0.45) | HDAC6HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6824912 | 0.79 | KDM4E (0.35) | HDAC1NPC1RAB9ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | claimed |
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | disclosed |