Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923084 | 0.98 | HDAC1 (0.46) | HDAC1TDP1POLBCNR1CNR2 | |
| SCHEMBL6825780 | 0.91 | HDAC1 (0.45) | HDAC1TDP1POLBCNR1CNR2 | |
| SCHEMBL6827728 | 0.89 | HDAC1 (0.47) | HDAC1TDP1POLBCNR1CNR2 | |
| SCHEMBL6825231 | 0.88 | HDAC6 (0.49) | HDAC1ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL6922062 | 0.88 | SMN1; SMN2 (0.38) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6825343 | 0.87 | HDAC1 (0.47) | HDAC1TDP1POLBKDRTP53 | |
| SCHEMBL6922133 | 0.86 | P2RX7 (0.45) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6824912 | 0.85 | KDM4E (0.35) | HDAC1 | |
| SCHEMBL6825337 | 0.84 | HDAC1 (0.48) | HDAC1TDP1POLBKDRMEN1 | |
| SCHEMBL6825435 | 0.83 | NPC1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | claimed |
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | disclosed |