Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827642 | 0.90 | NPC1 (0.38) | NPC1RAB9AEPHX2 | |
| SCHEMBL6822283 | 0.88 | TDP1 (0.43) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL6822311 | 0.88 | NPC1 (0.40) | NPC1RAB9AHDAC1HDAC6EPHX2 | |
| SCHEMBL6825944 | 0.88 | KMT2A (0.43) | NPC1RAB9AGAAHDAC1HDAC6 | |
| SCHEMBL6822302 | 0.88 | KMT2A (0.40) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6822411 | 0.86 | TDP1 (0.45) | ALDH1A1HPGDSMN1; SMN2LMNATDP1 | |
| SCHEMBL6822127 | 0.86 | KMT2A (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7065876 | 0.85 | KMT2A (0.44) | ALDH1A1SMN1; SMN2HSD17B10GAALMNA | |
| SCHEMBL7064899 | 0.85 | OPRM1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6826087 | 0.85 | KMT2A (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | claimed |