SCHEMBL681978

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL878088	1.00	HCRTR1 (0.40)	HCRTR1HCRTR2TRPC6PDE4AFFAR4
	SCHEMBL682585	0.93	PDE4B (0.44)	HCRTR1HCRTR2PDE4APDE4BKDM4E
	SCHEMBL877437	0.93	PDE4B (0.44)	HCRTR1HCRTR2PDE4APDE4BKDM4E
	SCHEMBL682749	0.91	PDE4B (0.46)	HCRTR1HCRTR2PDE4APDE4B
	SCHEMBL2134832	0.91	PDE4B (0.46)	HCRTR1HCRTR2PDE4APDE4B
	SCHEMBL681973	0.87	HCRTR1 (0.41)	HCRTR1HCRTR2TRPC6PDE4AFFAR4
	SCHEMBL877836	0.87	HCRTR1 (0.41)	HCRTR1HCRTR2TRPC6PDE4AFFAR4
	SCHEMBL878268	0.87	PDE4B (0.45)	HCRTR1HCRTR2TRPC6PDE4AFFAR4
	SCHEMBL683387	0.87	PDE4B (0.45)	HCRTR1HCRTR2TRPC6PDE4AFFAR4
	SCHEMBL876549	0.86	HCRTR1 (0.39)	HCRTR1HCRTR2TRPC6PDE4AFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.