Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468110 | 0.84 | BAZ2B (0.40) | L3MBTL1BAZ2BLRRK2KDM4EALDH1A1 | |
| SCHEMBL6826183 | 0.79 | AR (0.41) | BAZ2BLRRK2LMNAKDM4EALDH1A1 | |
| SCHEMBL31739403 | 0.79 | MALT1 (0.38) | BAZ2BLRRK2KDM4EALDH1A1 | |
| SCHEMBL4751927 | 0.77 | PLA2G10 (0.49) | PLA2G10L3MBTL1BAZ2BGSK3BFAAH | |
| SCHEMBL1080282 | 0.77 | BAZ2B (0.61) | PLA2G10L3MBTL1BAZ2BGSK3BPIM3 | |
| SCHEMBL24914934 | 0.76 | GAA (0.43) | L3MBTL1FAAHLMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3491832 | 0.76 | BAZ2B (0.59) | PLA2G10L3MBTL1BAZ2BGSK3BPIM3 | |
| SCHEMBL29092152 | 0.73 | PLA2G10 (0.49) | PLA2G10L3MBTL1BAZ2BGSK3BFAAH | |
| SCHEMBL15942241 | 0.73 | PLA2G10 (0.49) | PLA2G10L3MBTL1BAZ2BGSK3BFAAH | |
| SCHEMBL29080123 | 0.72 | PLA2G10 (0.47) | PLA2G10L3MBTL1BAZ2BGSK3BFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740647-B1 | AMIDINES AND HYDROXYAMIDINE DERIVATIVES | ABBOTT GMBH & CO., KG (DE) | 2004-05-25 | — | — | US | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| CN-1228783-A | Novel thrombin inhibitors | BASF AG (DE) | 1999-09-15 | — | — | CN | disclosed |