Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30287553 | 0.88 | MEN1 (0.40) | PLA2G10GSK3BMEN1KMT2ARXFP1 | |
| SCHEMBL5600063 | 0.88 | KDM4E (0.44) | PLA2G10MEN1KMT2ARXFP1L3MBTL1 | |
| SCHEMBL14351941 | 0.85 | PLA2G10 (0.44) | PLA2G10GSK3BMEN1KMT2ARXFP1 | |
| SCHEMBL18904958 | 0.83 | BAZ2B (0.53) | PLA2G10GSK3BMEN1KMT2ARXFP1 | |
| SCHEMBL7819956 | 0.83 | PLA2G10 (0.43) | PLA2G10GSK3BMEN1KMT2ARXFP1 | |
| SCHEMBL20455602 | 0.83 | MEN1 (0.42) | MEN1KMT2ARXFP1L3MBTL1KDM4E | |
| SCHEMBL24914933 | 0.79 | LMNA (0.51) | MEN1KMT2AKDM4ELMNAFAAH | |
| SCHEMBL15942241 | 0.79 | PLA2G10 (0.49) | PLA2G10GSK3BL3MBTL1KDM4EBAZ2B | |
| SCHEMBL4751927 | 0.79 | PLA2G10 (0.49) | PLA2G10GSK3BL3MBTL1KDM4EBAZ2B | |
| SCHEMBL16629260 | 0.79 | KDM4E (0.39) | PLA2G10MEN1KMT2ARXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | disclosed |