SCHEMBL6825907

SCHEMBL6825907

CN1CC[C@@H](Oc2cc(NS(=O)(=O)c3cc(Cl)c(-c4ccccc4)s3)ccc2C(F)(F)F)C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.57
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825909 1.00 UTS2R (0.57) UTS2RHTR6
SCHEMBL8338054 0.93 UTS2R (0.57) UTS2R
SCHEMBL6828664 0.93 UTS2R (0.57) UTS2R
SCHEMBL6828662 0.93 UTS2R (0.57) UTS2R
SCHEMBL8337868 0.92 UTS2R (0.56) UTS2RHTR6
SCHEMBL6829210 0.91 UTS2R (0.54) UTS2R
SCHEMBL6829204 0.91 UTS2R (0.54) UTS2R
SCHEMBL6828303 0.91 UTS2R (0.57) UTS2R
SCHEMBL6828553 0.91 UTS2R (0.55) UTS2R
SCHEMBL6828551 0.91 UTS2R (0.55) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed