SCHEMBL6828664

SCHEMBL6828664

Cc1ccc(-c2sc(S(=O)(=O)Nc3ccc(C(F)(F)F)c(OC4CCN(C)C4)c3)cc2Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.57
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
SGK1 O00141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828662 1.00 UTS2R (0.57) UTS2RHTR2CHTR2BSGK1
SCHEMBL8337868 0.93 UTS2R (0.56) UTS2R
SCHEMBL6825907 0.93 UTS2R (0.57) UTS2R
SCHEMBL6825909 0.93 UTS2R (0.57) UTS2R
SCHEMBL6830946 0.92 UTS2R (0.55) UTS2RHTR2C
SCHEMBL6830950 0.92 UTS2R (0.55) UTS2RHTR2C
SCHEMBL6828305 0.91 UTS2R (0.57) UTS2R
SCHEMBL6828303 0.91 UTS2R (0.57) UTS2R
SCHEMBL6828553 0.91 UTS2R (0.55) UTS2R
SCHEMBL6828551 0.91 UTS2R (0.55) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed