SCHEMBL682598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL873594	1.00	PDE4B (0.45)	PDE4BLMNAMEN1KMT2APDE4A
	SCHEMBL2142271	0.92	LMNA (0.48)	PDE4BLMNAPDE4ANR1H2NR1H3
	SCHEMBL683004	0.92	LMNA (0.48)	PDE4BLMNAPDE4ANR1H2NR1H3
	SCHEMBL2085028	0.92	PDE4A (0.50)	PDE4BLMNAPDE4ANR1H2NR1H3
	SCHEMBL682509	0.92	PDE4A (0.50)	PDE4BLMNAPDE4ANR1H2NR1H3
	SCHEMBL2087118	0.87	PDE4A (0.51)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL682635	0.87	PDE4A (0.51)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL682915	0.86	PDE4A (0.47)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL2087008	0.86	PDE4A (0.47)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL682512	0.85	PDE4B (0.46)	PDE4BLMNAPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.