Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101253 | 0.77 | CHRNA7 (0.45) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL26490 | 0.66 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL29412294 | 0.66 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL26491 | 0.66 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL237347 | 0.66 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL15757034 | 0.66 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL7735963 | 0.66 | CHRNA7 (0.60) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL30201546 | 0.65 | CHRNA7 (0.72) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| Thiacloprid SCHEMBL27503321 | 0.65 | CHRNA7 (0.98) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL5833216 | 0.64 | CHRNA7 (0.61) | CHRNA7MEN1KMT2ATDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385817-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090320-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |