Thiacloprid

Thiacloprid

SCHEMBL237347

N#C/N=C1/SCCN1Cc1ccc(Cl)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
CHRNA1 P02708 2/20 0.61
CHRNB2 P17787 2/20 0.52
CHRNA4 P43681 2/20 0.52
PDE4B Q07343 5/20 0.50
PDE4D Q08499 1/20 0.50
CHRNA3 P32297 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiacloprid SCHEMBL26490 1.00 CHRNA7 (1.00) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL26491 1.00 CHRNA7 (1.00) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL15757034 1.00 CHRNA7 (1.00) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL29412294 1.00 CHRNA7 (1.00) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL27503321 0.99 CHRNA7 (0.98) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL28027940 0.96 CHRNA7 (0.93) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL19032639 0.93 CHRNA7 (0.87) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL27978460 0.93 CHRNA7 (0.87) CHRNA7MEN1KMT2ATDP1CHRNA1
SCHEMBL18623489 0.88 CHRNA7 (0.78) CHRNA7MEN1KMT2ATDP1CHRNA1
Thiacloprid SCHEMBL28279814 0.87 KMT2A (0.76) CHRNA7MEN1KMT2ATDP1CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2751100-B1 METHOD FOR PRODUCING [3-[(6-CHLOR-3-PRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE BAYER IP GMBH (DE) 2015-10-14 EP claimed
US-20150005502-A1 PROCESS FOR PREPARING [3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-01 US claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20010004460-A1 PROCESS FOR THE PREPARATION OF RICE SEED FOR SOWING KLITTICH CARLA RASMUSSEN (US) 2001-06-21 US claimed
US-20230232833-A1 Synergistic Compositions for the Control of Mosquito-Borne Diseases UNIVERSITE D'ANGERS (FR) 2023-07-27 US disclosed
EP-4171229-A1 SYNERGISTIC COMPOSITIONS FOR THE CONTROL OF MOSQUITO-BORNE DISEASES UNIVERSITE D'ANGERS (FR) 2023-05-03 EP disclosed
WO-2022002928-A1 SYNERGISTIC COMPOSITIONS FOR THE CONTROL OF MOSQUITO-BORNE DISEASES UNIVERSITE D'ANGERS (FR) 2022-01-06 WO disclosed
US-11161840-B2 Process for producing heterocylic compounds BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-11-02 US disclosed
US-10874107-B2 β-lactamase targeted photosensitizer for pesticide and pest detection THE GENERAL HOSPITAL CORPORATION (US) 2020-12-29 US disclosed
US-20200154710-A1 BETA-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2020-05-21 US disclosed
US-20190045778-A1 EMULSIFIABLE CONCENTRATES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-14 US disclosed
WO-2017211594-A1 METHOD FOR PRODUCING HETEROCYCLIC COMPOUNDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-12-14 WO disclosed
WO-2000020415-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed
WO-2000018742-A1 SULFONYLTRIAZOL DERIVATIVES AND THEIR USE FOR COMBATING MICRO-ORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 2000-04-06 WO disclosed
WO-2000015620-A1 SULFONYL OXAZOLONES AND THEIR USE FOR COMBATING UNDESIRABLE MICROORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 2000-03-23 WO disclosed
WO-2000015622-A1 ISOTHIAZOLE CARBOXYLIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-23 WO disclosed
WO-2000014071-A2 PYRAZOLE CARBOXANILIDE FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2000-03-16 WO disclosed
WO-2000010970-A1 METHOXIMINOPHENYLACETIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-03-02 WO disclosed
WO-2000003995-A1 DIPHENYLIMIDAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 2000-01-27 WO disclosed
WO-1999016748-A1 UTILIZING SPIROCYCLIC PHENYL KETO-ENOLS AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874107-B2 β-lactamase targeted photosensitizer for pesticide and pest detection DDT, BCHE, GUSB CHRNA7 3271/4885MEN1 4071/4885KMT2A 953/4885
US-20190045778-A1 EMULSIFIABLE CONCENTRATES AQP1, ACHE, PHOSPHO1 CHRNA7 770/4885MEN1 2827/4885KMT2A 3902/4885
US-11161840-B2 Process for producing heterocylic compounds CYP1A1, CYP3A5, CYP1B1 CHRNA7 3095/4885MEN1 1086/4885KMT2A 819/4885
US-20200154710-A1 BETA-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION DDT, BCHE, GUSB CHRNA7 2770/4885MEN1 3967/4885KMT2A 1285/4885
US-20010004460-A1 PROCESS FOR THE PREPARATION OF RICE SEED FOR SOWING GYS2, POF1B, AGL CHRNA7 3367/4885MEN1 4566/4885KMT2A 3246/4885
US-20150005502-A1 PROCESS FOR PREPARING [3-[(6-CHLORO-3-PYRIDINYL)METHYL]-2-THIAZOLIDINYLIDENE]CYANAMIDE TPMT, AZI2, TYR CHRNA7 2433/4885MEN1 1456/4885KMT2A 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.