⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Octanol SCHEMBL6826944 | 1.00 | — | — | |
| 3-Octanol SCHEMBL112339 | 1.00 | — | — | |
| SCHEMBL6298504 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL14396082 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL378964 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL10436370 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL194832 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL2609783 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL22910980 | 0.97 | GPR84 (0.58) | — | |
| SCHEMBL378906 | 0.97 | GPR84 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390437-B2 | Itaconic acid derivatives and uses thereof intreating an inflammatory disease or a disease associated with an undesirable immune response | SITRYX THERAPEUTICS LIMITED (GB) | 2025-08-19 | — | — | US | disclosed |
| EP-3962602-B1 | ITACONIC ACID DERIVATIVES AND USES THEREOF IN TREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LTD (GB) | 2025-06-25 | — | — | EP | disclosed |
| US-20220265595-A1 | ITACONIC ACID DERIVATIVES AND USES THEREOF INTREATING AN INFLAMMATORY DISEASE OR A DISEASE ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-08-25 | — | — | US | disclosed |
| US-11369617-B2 | Prostacyclin analogue formulations | CAMURUS AB (SE) | 2022-06-28 | — | — | US | disclosed |
| US-20190255068-A1 | PROSTACYCLIN ANALOGUE FORMULATIONS | CAMURUS AB (SE) | 2019-08-22 | — | — | US | disclosed |
| WO-2018050864-A1 | PROSTACYCLIN ANALOGUE FORMULATIONS | CAMURUS AB (SE) | 2018-03-22 | — | — | WO | disclosed |
| US-9102660-B2 | Process of making prostacyclin compounds with linker thiol and pegylated forms | United Therapeutics Corporaiton (US) | 2015-08-11 | — | — | US | disclosed |
| WO-2014160638-A1 | PROCESS OF MAKING PROSTACYCLIN COMPOUNDS WITH LINKER THIOL AND PEGYLATED FORMS | UNITED THERAPEUTICS CORPORATION (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140288314-A1 | PROCESS OF MAKING PROSTACYCLIN COMPOUNDS WITH LINKER THIOL AND PEGYLATED FORMS | UNITED THERAPEUTICS CORPORATION (US) | 2014-09-25 | — | — | US | disclosed |
| US-20130210704-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2013-08-15 | — | — | US | disclosed |
| CN-1278675-C | Granular material comprising polyhydroxyalkanoate and method for producing the same | CANON KK (JP) | 2006-10-11 | — | — | CN | disclosed |
| WO-2004111041-A1 | PYRROLIDINE, THIAZOLIDINE AND OXAZOLIDINE COMPOUNDS WHICH INHIBIT DIPEPTIDYL PEPTIDASE-IV (DPP) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-23 | — | — | WO | disclosed |
| CN-1431041-A | Granular material comprising polyhydroxyalkanoate and method for producing the same | CANON KK (JP) | 2003-07-23 | — | — | CN | disclosed |
| CN-1028033-C | Naphthalene compound and liquid crystal composition containing the same | MITSUI PETROCHEMICAL IND (JP) | 1995-03-29 | — | — | CN | disclosed |
| US-5385833-A | Enzymatic synthesis of alcohols from carbonyl compounds | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-01-31 | — | — | US | disclosed |
| US-5230802-A | Liquid ion exchanger of alkyl 2,3-bis(alkanoyloxy)butanediote and ion exchange process | PHILIP MORRIS INCORPORATED (US) | 1993-07-27 | — | — | US | disclosed |
| US-5141668-A | NAPHTHALENE COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| CN-1038275-A | Naphthalene compound and contain the liquid-crystal composition of this thing | MITSUI PETROCHEMICAL IND (JP) | 1989-12-27 | — | — | CN | disclosed |
| EP-0341922-A2 | Naphthalene compound and liquid crystal composition containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |