Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828688 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6826652 | 0.80 | ABCB1 (0.54) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6828569 | 0.79 | BRAF (0.54) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL17396514 | 0.78 | KDM4E (0.72) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL31219113 | 0.78 | KDM4E (0.72) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6826964 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6822894 | 0.77 | POLB (0.55) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6827207 | 0.76 | MAPT (0.60) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL18496507 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1MAPTMAPK1POLB | |
| SCHEMBL6826428 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1MAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111052-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE (MDR) | XENOVA LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |