Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826750 | 1.00 | BTK (0.56) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL6826744 | 1.00 | BTK (0.56) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL15688768 | 0.92 | BTK (0.48) | BTKL3MBTL1KMT2AEPHX1ALDH1A1 | |
| SCHEMBL18896411 | 0.92 | BTK (0.48) | BTKL3MBTL1KMT2AEPHX1ALDH1A1 | |
| SCHEMBL6878689 | 0.88 | BTK (0.59) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL6878687 | 0.88 | BTK (0.59) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL6878692 | 0.88 | BTK (0.59) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL21211377 | 0.88 | BTK (0.44) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL15285429 | 0.88 | BTK (0.44) | BTKL3MBTL1KMT2AEPHX1CA1 | |
| SCHEMBL6883712 | 0.84 | BTK (0.65) | BTKL3MBTL1KMT2AEPHX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | ASTRAZENECA AB (SE) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | NPY5R, NPY1R, NPY2R | BTK 1214/4885L3MBTL1 3476/4885KMT2A 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.