⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341929 | 0.75 | — | — | |
| SCHEMBL21227022 | 0.75 | — | — | |
| SCHEMBL19003153 | 0.74 | — | — | |
| SCHEMBL341390 | 0.73 | CYP2C19 (0.30) | — | |
| SCHEMBL4297297 | 0.70 | — | — | |
| SCHEMBL20730066 | 0.69 | CYP4F2 (0.35) | — | |
| SCHEMBL8607807 | 0.67 | EPHX1 (0.39) | — | |
| SCHEMBL9730144 | 0.67 | — | — | |
| SCHEMBL6826782 | 0.64 | — | — | |
| SCHEMBL16370047 | 0.64 | CYP2C19 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | ASTRAZENECA AB (SE) | 2004-04-08 | — | — | US | disclosed |
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |
| EP-0129773-B1 | INSECTICIDAL CARBAMATES | BASF Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4537901-A | MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0129773-A2 | Insecticidal carbamates | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | disclosed |