Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214313 | 0.87 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL19112326 | 0.87 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL8610401 | 0.84 | — | — | |
| SCHEMBL24615828 | 0.82 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL34476200 | 0.82 | EPHX1 (0.30) | EPHX1 | |
| SCHEMBL24015967 | 0.76 | TSHR (0.33) | EPHX1 | |
| SCHEMBL27209939 | 0.76 | — | — | |
| SCHEMBL9516701 | 0.76 | EPHX1 (0.43) | EPHX1KDM4EALDH1A1 | |
| SCHEMBL14016141 | 0.75 | — | — | |
| SCHEMBL4562973 | 0.75 | USP2 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821391-A | HYDROGENATING 1,3-DIOXANES IN THE PRESENCE OF A CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5780686-A | REACTING 1,3-DIOXANES WITH AMMONIA AND HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5780687-A | REACTING 1,3-DIOXANES WITH HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0810194-A1 | Process for preparing 3-oxyalkylpropan-1-ols | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0810202-A2 | Process for the preparation of 4-oxaamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0316672-B1 | PROCESS FOR THE PREPARATION OF GLYOXAL MONOACETALS | BASF Aktiengesellschaft (DE) | 1993-06-09 | — | — | EP | disclosed |