Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824182 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL7191986 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL6923726 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL6824892 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL6821089 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL7067860 | 0.77 | HRH3 (0.52) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| Acetic Acid SCHEMBL7169485 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL6139577 | 0.74 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL6821107 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL5211150 | 0.74 | HRH3 (0.61) | ALDH1A1KDM4EPOLBHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |