Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827261 | 0.89 | MAPT (0.38) | MAPT | |
| SCHEMBL6829521 | 0.85 | CYP1B1 (0.38) | DAOMAPT | |
| SCHEMBL6829397 | 0.84 | CYP1B1 (0.40) | DAOMAPT | |
| SCHEMBL6827962 | 0.79 | TDP1 (0.47) | DAOMAPTKDM5BRECQL | |
| SCHEMBL6829594 | 0.77 | MAPT (0.34) | DAOMAPT | |
| SCHEMBL6824261 | 0.73 | PRKDC (0.41) | DAO | |
| SCHEMBL6824851 | 0.71 | CYP1B1 (0.40) | MAPT | |
| SCHEMBL24270199 | 0.69 | DAO (0.37) | DAOMAPT | |
| SCHEMBL4773892 | 0.66 | DAO (0.35) | DAOMAPTKDM5B | |
| SCHEMBL1263377 | 0.66 | TDP1 (0.53) | MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |