Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17292515 | 0.92 | CYP1B1 (0.35) | MAPTCYP1B1CYP1A1PLGGABRA1 | |
| SCHEMBL6829521 | 0.92 | CYP1B1 (0.38) | MAPTCYP1B1TDP1 | |
| SCHEMBL6829397 | 0.90 | CYP1B1 (0.40) | MAPTCYP1B1TDP1 | |
| SCHEMBL6827176 | 0.89 | DAO (0.39) | MAPT | |
| SCHEMBL6829594 | 0.87 | MAPT (0.34) | MAPTMAOAMAOB | |
| SCHEMBL6824851 | 0.77 | CYP1B1 (0.40) | MAPTCYP1B1CYP1A2 | |
| SCHEMBL1263377 | 0.75 | TDP1 (0.53) | MAPTCYP1B1CYP1A1CYP1A2PLG | |
| SCHEMBL6827164 | 0.69 | NPC1 (0.41) | MAPTCYP1B1CYP1A1CYP1A2GABRA1 | |
| SCHEMBL17292459 | 0.68 | TDP1 (0.50) | MAPTCYP1B1CYP1A2MAOBTDP1 | |
| SCHEMBL6829613 | 0.68 | TDP1 (0.50) | MAPTCYP1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |