Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861386 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL4042099 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL3539282 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL4042106 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL5620017 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL5620023 | 0.83 | ATM (0.48) | CTSKCTSLALDH1A1ALOX15TSHR | |
| SCHEMBL7797923 | 0.76 | KDM4E (0.43) | CTSKCTSLALDH1A1CASP1CASP3 | |
| SCHEMBL9058778 | 0.76 | ATM (0.45) | CTSKCTSL | |
| SCHEMBL9472908 | 0.76 | ATM (0.45) | CTSKCTSL | |
| SCHEMBL9296151 | 0.74 | ATM (0.47) | CTSKCTSLALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111022-A1 | 3-(1,1-DIOXOTETRAHYDRO-1,2-THIAZIN-2-YL) or 3-(1,1-DOXO-ISOTHIAZOLIDIN-2YL) SUBSTITUTED BENZAMIDE COMPOUNDS AS ASP2 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |