Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151399 | 0.80 | USP2 (0.49) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL2323987 | 0.80 | USP2 (0.53) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL3448446 | 0.78 | KCNN4 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL6627229 | 0.77 | USP2 (0.46) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL149631 | 0.77 | ALDH1A1 (0.49) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL10500375 | 0.77 | USP2 (0.50) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL6114723 | 0.77 | USP2 (0.46) | USP2HSD17B10MLYCDALDH1A1MEN1 | |
| SCHEMBL2243707 | 0.76 | NPSR1 (0.44) | USP2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27929156 | 0.76 | ALDH1A1 (0.40) | USP2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL13158975 | 0.75 | TDP1 (0.42) | HSD17B10MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009559-A2 | DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-01-29 | — | — | WO | disclosed |