Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769439 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL31442821 | 0.81 | KDM4E (0.47) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6607686 | 0.80 | MAPT (0.41) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL27178872 | 0.76 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7840126 | 0.76 | MEN1 (0.50) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL994347 | 0.74 | ALDH1A1 (0.68) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29536266 | 0.74 | ALDH1A1 (0.68) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL23783057 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL30207467 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL10189346 | 0.73 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058727-A1 | SUBSTITUTED 3,5-DIHYDRO-4H-IMIDAZOL-4-ONES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |