Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 8/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349824 | 0.81 | MCHR1 (0.45) | TLR8MCHR1FFAR1CYP2D6IGF1R | |
| SCHEMBL27315842 | 0.80 | ADRB2 (0.51) | TLR8MCHR1KDM4EPKMADRB2 | |
| SCHEMBL8219663 | 0.75 | ESR2 (0.45) | TLR8MCHR1FFAR1GPR88CYP2D6 | |
| SCHEMBL14364260 | 0.75 | MCHR1 (0.45) | TLR8MCHR1FFAR1IGF1RKDM4E | |
| SCHEMBL19056886 | 0.74 | CYP1A2 (0.45) | TLR8KDM4EADRB2 | |
| SCHEMBL5649980 | 0.73 | TLR8 (0.54) | TLR8MCHR1FFAR1IGF1RKDM4E | |
| SCHEMBL10905811 | 0.72 | EGFR (0.53) | FFAR1KDM4EPKM | |
| SCHEMBL10349822 | 0.72 | TLR8 (0.50) | TLR8MCHR1FFAR1IGF1RKDM4E | |
| SCHEMBL10429752 | 0.71 | FFAR1 (0.39) | TLR8FFAR1GPR88CYP2D6KDM4E | |
| SCHEMBL31644115 | 0.70 | MGAM (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |