SCHEMBL682747

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2140445	1.00	PDE4B (0.44)	PDE4BPDE4DCYP3A4CYP2D6SLC5A7
	SCHEMBL877075	0.98	CYP3A4 (0.43)	PDE4BPDE4DCYP3A4CYP2D6SLC5A7
	SCHEMBL877074	0.98	CYP3A4 (0.43)	PDE4BPDE4DCYP3A4CYP2D6SLC5A7
	SCHEMBL2134832	0.92	PDE4B (0.46)	PDE4BPDE4DPDE4APDE4CNR1H2
	SCHEMBL682749	0.92	PDE4B (0.46)	PDE4BPDE4DPDE4APDE4CNR1H2
	SCHEMBL681959	0.91	PDE4A (0.50)	PDE4BPDE4DPDE4APDE4C
	SCHEMBL2138265	0.91	PDE4A (0.50)	PDE4BPDE4DPDE4APDE4C
	SCHEMBL683043	0.91	PDE4A (0.43)	PDE4BPDE4DSLC5A7PDE4APDE4C
	SCHEMBL2136949	0.91	PDE4A (0.43)	PDE4BPDE4DSLC5A7PDE4APDE4C
	SCHEMBL683366	0.90	KDM4E (0.41)	CYP3A4CYP2D6SLC5A7DPP4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.